Fibrin structure and wound healing.

  title={Fibrin structure and wound healing.},
  author={Nancy Laurens and Pieter Koolwijk and Moniek P M de Maat},
  journal={Journal of thrombosis and haemostasis : JTH},
  volume={4 5},
Fibrinogen and fibrin play an important role in blood clotting, fibrinolysis, cellular and matrix interactions, inflammation, wound healing, angiogenesis, and neoplasia. The contribution of fibrin(ogen) to these processes largely depends not only on the characteristics of the fibrin(ogen) itself, but also on interactions between specific-binding sites on fibrin(ogen), pro-enzymes, clotting factors, enzyme inhibitors, and cell receptors. In this review, the molecular and cellular biology of… CONTINUE READING