Fibrin formation by wounded bronchial epithelial cell layers in vitro is essential for normal epithelial repair and independent of plasma proteins.

@article{Perrio2007FibrinFB,
  title={Fibrin formation by wounded bronchial epithelial cell layers in vitro is essential for normal epithelial repair and independent of plasma proteins.},
  author={M J Perrio and Danielle T. Ewen and Mike A Trevethick and Gary P. Salmon and Janis K Shute},
  journal={Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology},
  year={2007},
  volume={37 11},
  pages={
          1688-700
        }
}
BACKGROUND The bronchial epithelium is in contact with, and continually damaged by, the environment. Animal models have indicated that normal epithelial repair is rapid and supported by the formation of a provisional fibrin matrix that is exclusively plasma-derived. OBJECTIVES Our objectives were to demonstrate the ability of normal human bronchial epithelial (NHBE) cells to produce coagulation cascade proteins and form fibrin in response to damage, independently of plasma proteins, and to… CONTINUE READING
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