Fibrin content of carotid thrombi alters the production of embolic stroke in the rat.

BACKGROUND AND PURPOSE Mechanical denudation of the endothelium of the carotid artery in animals produces a nonocclusive thrombus, but the brains of these animals have not been examined for the presence of embolic stroke. METHODS The endothelium of the right carotid artery of 16 Wistar rats was denuded using a balloon catheter. Phosphotungstic acid… CONTINUE READING