Fibrin and poly(lactic-co-glycolic acid) hybrid scaffold promotes early chondrogenesis of articular chondrocytes: an in vitro study

@article{Shaban2008FibrinAP,
  title={Fibrin and poly(lactic-co-glycolic acid) hybrid scaffold promotes early chondrogenesis of articular chondrocytes: an in vitro study},
  author={M. Sha'ban and Soon Hee Kim and Ruszymah BH Idrus and Gilson Khang},
  journal={Journal of Orthopaedic Surgery and Research},
  year={2008},
  volume={3},
  pages={17 - 17}
}
BACKGROUND Synthetic- and naturally derived- biodegradable polymers have been widely used to construct scaffolds for cartilage tissue engineering. Poly(lactic-co-glycolic acid) (PLGA) are bioresorbable and biocompatible, rendering them as a promising tool for clinical application. To minimize cells lost during the seeding procedure, we used the natural polymer fibrin to immobilize cells and to provide homogenous cells distribution in PLGA scaffolds. We evaluated in vitro chondrogenesis of… CONTINUE READING