Fibrin II induces endothelial cell capillary tube formation

@article{Chalupowicz1995FibrinII,
  title={Fibrin II induces endothelial cell capillary tube formation},
  author={D G Chalupowicz and Z A Chowdhury and Tami L Bach and Carl Barsigian and Jean Martinez},
  journal={The Journal of Cell Biology},
  year={1995},
  volume={130},
  pages={207 - 215}
}
We studied the formation of capillary tubes by endothelial cells which were sandwiched between two fibrin gels under serum-free conditions. After formation of the overlying fibrin gel, the endothelial cell monolayer rearranged into an extensive net of capillary tubes. Tube formation was apparent at 5 h and was fully developed by 24 h. The capillary tubes were vacuolated, and both intracellular and intercellular lumina were present. Maximal tube formation was observed with fibrin II (which lacks… CONTINUE READING

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References

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Showing 1-10 of 41 references

Regulation of in vitro capillary tube formation by anti-integrin antibodies

The Journal of cell biology • 1993
View 9 Excerpts
Highly Influenced

214 vascular integrin etv133 for angiogenesis

P. C. Brooks, g. A.F. Clark, D. A. Cheresh
Requirement of The Journal of Cell Biology, Volume 130, • 1994
View 4 Excerpts
Highly Influenced

Angiogenesis in vitro

View 4 Excerpts
Highly Influenced

Vascular endothelial growth factor.

European journal of cancer • 1996

Angiogenesis and breast cancer.

Journal of clinical oncology : official journal of the American Society of Clinical Oncology • 1994
View 2 Excerpts

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