FiberDock: a web server for flexible induced-fit backbone refinement in molecular docking

@inproceedings{Mashiach2010FiberDockAW,
  title={FiberDock: a web server for flexible induced-fit backbone refinement in molecular docking},
  author={Efrat Mashiach and Ruth Nussinov and Haim J. Wolfson},
  booktitle={Nucleic Acids Research},
  year={2010}
}

• Efrat Mashiach, Ruth Nussinov, Haim J. Wolfson
• Published 2010 in Nucleic Acids Research
• DOI:10.1093/nar/gkq373

Protein-protein docking algorithms aim to predict the structure of a complex given the atomic structures of the proteins that assemble it. The docking procedure usually consists of two main steps: docking candidate generation and their refinement. The refinement stage aims to improve the accuracy of the candidate solutions and to identify near-native solutions among them. During protein-protein interaction, both side chains and backbone change their conformation. Refinement methods should model… CONTINUE READING

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