Fiber optic microneedles for transdermal light delivery: ex vivo porcine skin penetration experiments.

@article{Kosoglu2010FiberOM,
  title={Fiber optic microneedles for transdermal light delivery: ex vivo porcine skin penetration experiments.},
  author={Mehmet A. Kosoglu and Robert Lyle Hood and Ye Chen and Yong Xu and Marissa Nichole Rylander and Christopher G. Rylander},
  journal={Journal of biomechanical engineering},
  year={2010},
  volume={132 9},
  pages={091014}
}
Shallow light penetration in tissue has been a technical barrier to the development of light-based methods for in vivo diagnosis and treatment of epithelial carcinomas. This problem can potentially be solved by utilizing minimally invasive probes to deliver light directly to target areas. To develop this solution, fiber optic microneedles capable of delivering light for either imaging or therapy were manufactured by tapering step-index silica-based optical fibers employing a melt-drawing… CONTINUE READING