Fexofenadine: biochemical, pharmacokinetic and pharmacodynamic properties and its unique role in allergic disorders

  title={Fexofenadine: biochemical, pharmacokinetic and pharmacodynamic properties and its unique role in allergic disorders},
  author={S. M. Smith and J. Gums},
  journal={Expert Opinion on Drug Metabolism & Toxicology},
  pages={813 - 822}
Background: Fexofenadine is one of several second-generation H1-antihistamines approved for the treatment of various allergic disorders; however, it shows numerous unique properties that make it an optimal choice for many patients. Objective: To review the pharmacology, efficacy and safety of fexofenadine and the attributes differentiating it from other H1-antihistamines. Methods: We performed a literature search in PubMed/MEDLINE (1966 – March 2009) using the keywords fexofenadine… Expand
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