Fever in Children and Fever of Unknown Origin

@article{Dayal2015FeverIC,
  title={Fever in Children and Fever of Unknown Origin},
  author={R. Dayal and D. Agarwal},
  journal={The Indian Journal of Pediatrics},
  year={2015},
  volume={83},
  pages={38-43}
}
Fever is the most common symptom in children and can be classified as fever with or without focus. Fever without focus can be less than 7 d and is subclassified as fever without localizing signs and fever of unknown origin (FUO). FUO is defined as a temperature greater than 38.3 °C, for more than 3 wk or failure to reach a diagnosis after 1 wk of inpatient investigations. The most common causes of FUO in children are infections, connective tissue disorders and neoplasms. Infectious diseases… Expand
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Etiology and clinical characteristics of fever of unknown origin in children: a 15-year experience in a single center
TLDR
Investigation of the etiology, clinical characteristics and prognosis of pediatric FUO in 21 century with more diagnostics available and to analyze the factors for certain disease categories finds undiagnosed portion of F UO have now increased due to development of diagnostic techniques for infectious diseases. Expand
Fever of unknown origin - a literature review.
TLDR
The objective of this study is to review the main topics about fever of undetermined origin, bringing historical and scientific aspects, national and international, to review. Expand
childhood fever of unknown origin ( FUO ) – a
  • 2019
Rheumatological illnesses are common differential diagnosis in the evaluation of childhood fever of unknown origin (FUO). We report an 11-year-old female child referred as FUO for eight months,… Expand
Fever of unknown origin in special groups.
TLDR
The initial diagnostic approach of the FUO patient should include non-specific complementary exams, and empirical therapy is not recommended (with few exceptions), as it may disguise and delay the diagnosis and conduct to treat the specific etiology. Expand
Etiology of fever of unknown origin in children.
TLDR
Infectious diseases were the most common cause of FUO followed by malignancy, connective tissue disorders and miscellaneous causes, and there was a significant association between duration of fever and the ultimate diagnosis. Expand
TNFRSF1A gene variant identified in a boy with recurrent episodes of fever
TLDR
A boy with recurrent fever of unknown origin who was by clinically guided partial exome sequencing found to have a heterozygous variant 434A>G in the TNFRSF1A gene, otherwise connected with tumor necrosis factor receptor-associated periodic fever syndrome is presented. Expand
PET/Computed Tomography in the Evaluation of Fever of Unknown Origin and Infectious/Inflammatory Disease in Pediatric Patients.
TLDR
FDG-PET/CT is being increasingly used for investigation of FUO as well as infectious/inflammatory disease and often locates inflammatory and infectious lesions considered nonspecific or false-positive for oncology. Expand
Pediatric Spinal Epidural Abscess: A Case Report of a 12-year-old Girl Without Risk Factors
TLDR
Despite its irradiation to the patient, CT might be useful for providing an early diagnosis in the absence of neurologic symptoms, and whole-body CT later diagnosed a SEA, which was treated by antibiotics only. Expand
Fever without a source in children with congenital heart disease
TLDR
Infective endocarditis should be considered in any paediatric congenital congenital heart disease patient who presents with fever without any other associated clinical features. Expand
Polymyositis secondary to tuberculosis in an 11-year-old boy
TLDR
The case of an 11-year-old boy with polymyositis secondary to tuberculosis had an adequate response to corticosteroids, but these were not needed after the diagnosis of a Mycobacterium tuberculosis lung infection. Expand
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