Fetal undernutrition is associated with perinatal sex-dependent alterations in oxidative status.

@article{RodrguezRodrguez2015FetalUI,
  title={Fetal undernutrition is associated with perinatal sex-dependent alterations in oxidative status.},
  author={Pilar Rodr{\'i}guez-Rodr{\'i}guez and Angel Luis L{\'o}pez de Pablo and Luis Condezo-Hoyos and Mar{\'i}a Angeles Mart{\'i}n-Cabrejas and Yolanda Aguilera and Gema Ru{\'i}z-Hurtado and Perla Yareli Guti{\'e}rrez-Arzapalo and David Ramiro-Cortijo and Mar{\'i}a Soledad Fern{\'a}ndez-Alfonso and Mar{\'i}a Del Carmen S{\'a}enz Gonz{\'a}lez and Silvia M Arribas},
  journal={The Journal of nutritional biochemistry},
  year={2015},
  volume={26 12},
  pages={1650-9}
}
Intrauterine growth retardation predisposes to hypertension development, known as fetal programming. Females are less susceptible, which has been mainly attributed to estrogen influence. We hypothesize that perinatal differences in oxidative status might also contribute. We studied 21-day-old (prepuberal) and 6-month-old male and female offspring from rats fed ad libitum during gestation (Control) or with 50% of Control daily intake from day 10 to delivery (maternal undernutrition, MUN). We… CONTINUE READING

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