Fetal tissue transplants in animal models of Huntington’s disease: the effects on damaged neuronal circuitry and behavioral deficits

@article{Nakao2000FetalTT,
  title={Fetal tissue transplants in animal models of Huntington’s disease: the effects on damaged neuronal circuitry and behavioral deficits},
  author={Naoyuki Nakao and Toru Itakura},
  journal={Progress in Neurobiology},
  year={2000},
  volume={61},
  pages={313-338}
}
Accumulating evidence indicates that grafts of embryonic neurons achieve the anatomical and functional reconstruction of damaged neuronal circuitry. The restorative capacity of grafted embryonic neural tissue is most illustrated by studies with striatal tissue transplantation in animals with striatal lesions. Striatal neurons implanted into the lesioned striatum receive some of the major striatal afferents such as the nigrostriatal dopaminergic inputs and the gluatmatergic afferents from the… CONTINUE READING

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