Fetal protection in heifers vaccinated with a modified-live virus vaccine containing bovine viral diarrhea virus subtypes 1a and 2a and exposed during gestation to cattle persistently infected with bovine viral diarrhea virus subtype 1b.

@article{Leyh2011FetalPI,
  title={Fetal protection in heifers vaccinated with a modified-live virus vaccine containing bovine viral diarrhea virus subtypes 1a and 2a and exposed during gestation to cattle persistently infected with bovine viral diarrhea virus subtype 1b.},
  author={Randy D. Leyh and Robert W. Fulton and Jacob E Stegner and Michael D. Goodyear and Steven Witte and Lucas Taylor and Bill J. Johnson and Douglas L. Step and Julia F. Ridpath and Ben Patrick Holland},
  journal={American journal of veterinary research},
  year={2011},
  volume={72 3},
  pages={
          367-75
        }
}
OBJECTIVE To determine efficacy of a modified-live virus (MLV) vaccine containing bovine viral diarrhea virus (BVDV) 1a and 2a against fetal infection in heifers exposed to cattle persistently infected (PI) with BVDV subtype 1 b. ANIMALS 50 heifers and their fetuses. PROCEDURES Susceptible heifers received a placebo vaccine administered IM or a vaccine containing MLV strains of BVDV1a and BVDV2a administered IM or SC. On day 124 (64 to 89 days of gestation), 50 pregnant heifers (20… CONTINUE READING

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