Fetal or neonatal low-glycotoxin environment prevents autoimmune diabetes in NOD mice.


Advanced glycation end products (AGEs) are implicated in beta-cell oxidant stress. Diet-derived AGE (dAGE) are shown to contribute to end-organ toxicity attributed to diabetes. To assess the role of dAGE on type 1 diabetes, NOD mice were exposed to a high-AGE diet (H-AGE) and to a nutritionally similar diet with approximate fivefold-lower levels of N… (More)


8 Figures and Tables

Blog articles referencing this paper

Slides referencing similar topics