Fetal-maternal microchimerism: impact on hematopoietic stem cell transplantation.

  title={Fetal-maternal microchimerism: impact on hematopoietic stem cell transplantation.},
  author={T. Ichinohe and T. Teshima and K. Matsuoka and E. Maruya and Hiroh Saji},
  journal={Current opinion in immunology},
  volume={17 5},
  • T. Ichinohe, T. Teshima, +2 authors Hiroh Saji
  • Published 2005
  • Medicine, Biology
  • Current opinion in immunology
  • Reciprocal cell traffic between mother and fetus during pregnancy gives rise to postpartum fetal-maternal lymphohematopoietic microchimerism, which is frequently detected in blood or tissue from healthy individuals. Although such microchimerism has been implicated in the pathogenesis of autoimmune diseases and tissue repair, recent clinical experiences have suggested the association of microchimerism with acquired immunologic hyporesponsiveness to non-inherited maternal HLA antigens (NIMAs) or… CONTINUE READING
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