Fetal expression of GnRH and GnRH receptor genes in rat testis and ovary.

@article{Botte1998FetalEO,
  title={Fetal expression of GnRH and GnRH receptor genes in rat testis and ovary.},
  author={Manuela Botte and A M Chamagne and Murielle Carre and Raymond Counis and Marie Laure Kottler},
  journal={The Journal of endocrinology},
  year={1998},
  volume={159 1},
  pages={179-89}
}
The identification of gonadal gonadotropin-releasing hormone receptors (GnRH-R) and evidence of direct inhibitory effects of GnRH agonists upon steroidogenesis in adult rat gonads, lend credence to a putative intragonadal role of a locally secreted GnRH or GnRH-like peptide. Using reverse transcription-polymerase chain reaction followed by Southern blot hybridization and sequencing, we identified, both in the ovary and in the testis of fetal and adult rats, a fully processed GnRH messenger RNA… CONTINUE READING

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