Fetal exposure to placental corticotropin-releasing hormone (pCRH) programs developmental trajectories.

@article{Sandman2015FetalET,
  title={Fetal exposure to placental corticotropin-releasing hormone (pCRH) programs developmental trajectories.},
  author={Curt A. Sandman},
  journal={Peptides},
  year={2015},
  volume={72},
  pages={145-53}
}
The maternal endocrine stress system is profoundly altered during the course of human pregnancy. The human placenta expresses the genes for CRH as early as the seventh week of gestation and it is the expotential increase in placental CRH (pCRH) over the course of human gestation that is responsible for the greatest modification in the maternal stress system. The bi-directional placental release of hormones into the maternal and fetal compartments has profound influences for both. The… CONTINUE READING