Fetal exposure to DES results in de-regulation of Wnt7a during uterine morphogenesis

@article{Miller1998FetalET,
  title={Fetal exposure to DES results in de-regulation of Wnt7a during uterine morphogenesis},
  author={Cary Miller and Karl R Degenhardt and David A Sassoon},
  journal={Nature Genetics},
  year={1998},
  volume={20},
  pages={228-230}
}
228 nature genetics volume 20 november 1998 presence of a mosaic karyotype (Table 1). Therefore, although some functionally dicentric dic(X)s show retarded segregation during mitosis, they are not inherently unstable and must, in most instances, overcome the evident anaphase lag. We propose that the mosaicism associated with most cases of dic(X) reflects chromosome malsegregation and loss at the time of dicentric formation, rather than an ongoing instability. Our findings indicate several… CONTINUE READING

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