Fetal ethanol exposure attenuates aversive oral effects of TrpV1, but not TrpA1 agonists in rats.

@article{Glendinning2012FetalEE,
  title={Fetal ethanol exposure attenuates aversive oral effects of TrpV1, but not TrpA1 agonists in rats.},
  author={John I Glendinning and Yael M Simons and Lisa M Youngentob and Steven L. Youngentob},
  journal={Experimental biology and medicine},
  year={2012},
  volume={237 3},
  pages={236-40}
}
In humans, fetal ethanol exposure is highly predictive of adolescent ethanol use and abuse. Prior work in our labs indicated that fetal ethanol exposure results in stimulus-induced chemosensory plasticity in the taste and olfactory systems of adolescent rats. In particular, we found that increased ethanol acceptability could be attributed, in part, to an attenuated aversion to ethanol's aversive odor and quinine-like bitter taste quality. Here, we asked whether fetal ethanol exposure also… CONTINUE READING

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