Fetal endoscopic myelomeningocele repair

@article{Shurtleff2012FetalEM,
  title={Fetal endoscopic myelomeningocele repair},
  author={David B. Shurtleff},
  journal={Developmental Medicine \& Child Neurology},
  year={2012},
  volume={54}
}
  • D. Shurtleff
  • Published 1 January 2012
  • Medicine
  • Developmental Medicine & Child Neurology
The interesting paper by Verbeek et al. describes two separate technological advances applied to myelomeningocele. The first, muscle ultrasound density, is not evident in either the title of the article or the conclusion. It has the potential of being useful in distinguishing between toxicity from late gestational amniotic fluid to exposed nerves and the trauma of delivery. To do so would require comparing patients with prenatally repaired myelomeningocele lesions to children with… Expand

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Current knowledge about spina bifida and the potential benefits of prenatal surgery is summarized to gain a good understanding of the major advantages and disadvantages of the various surgical approaches. Expand
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References

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19-year follow-up of fetal myelomeningocele brought to term.
TLDR
A 19-year follow-up study of 223 infants with myelomeningocele born by cephalic presentation, 68 born by pre-rupture of amniotic membranes cesarean section and 155 born vaginally to determine outcome, there was no difference in the muscle strength loss between the PRAM C/S and the vaginally delivered groups. Expand
Fetal surgery for myelomeningocele
TLDR
Prenatal repair of myelomeningocele has been performed in the United States for 5 years with mixed results and serendipitously led to an apparent reduction in hindbrain herniation and a possible decreased need for ventriculoperitoneal shunting. Expand
Creation of myelomeningocele in utero: a model of functional damage from spinal cord exposure in fetal sheep.
TLDR
The goal of this study was to test whether chronic exposure of the normal spinal cord to the amniotic space produces a lesion similar to human MMC. Expand
Meningomyelocele: management in utero and post natum.
TLDR
The number of new cases of meningomyelocele presenting to the authors' clinic has decreased from an average of 30 per year between 1970 and 1987 to 14 between 1988 and 1992. Expand
Cesarean section before the onset of labor and subsequent motor function in infants with meningomyelocele diagnosed antenatally.
TLDR
For the fetus with uncomplicated meningomyelocele, delivery by cesarean section before the onset of labor may result in better subsequent motor function than vaginal delivery or delivery by trolley section after a period of labor. Expand
Modifications to the Traditional Description of Neurosegmental Innervation in Myelomeningocele
TLDR
It was found that medial hamstring strength more frequently correlated with iliopsoas and quadriceps, and glutei with anterior tibialis, and it is proposed that children with myelomeningocele be grouped according to specific muscle strength rather than by neurosegmental level. Expand
Spinal lesion level in spina bifida: a source of neural and cognitive heterogeneity.
TLDR
A higher level of spinal lesion in SBM-H is a marker for more severe anomalous brain development, which is in turn associated with poorer neurobehavioral outcomes in a wide variety of domains that determine levels of independent functioning for these children at home and school. Expand
Fetal endoscopic myelomeningocele closure preserves segmental neurological function
Aim  Our aim was to compare the effect of prenatal endoscopic with postnatal myelomeningocele closure (fetally operated spina bifida aperta [fSBA]) versus neonatally operated spina bifida apertaExpand
Letter to the Editor
The authors should be complimented for bringing to the attention of those working with spinal cord injury patients the unusual feature of self-biting of fingers in tetraplegic patients (Dahlin exExpand
Muscle ultrasound in neuromuscular disorders
TLDR
A major advantage of muscle ultrasound, compared to other imaging techniques, is its ability to visualize muscle movements, such as muscle contractions and fasciculations. Expand
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