Fetal development after transfer is increased by replacing protein with the glycosaminoglycan hyaluronan for mouse embryo culture and transfer.

@article{Gardner1999FetalDA,
  title={Fetal development after transfer is increased by replacing protein with the glycosaminoglycan hyaluronan for mouse embryo culture and transfer.},
  author={David K Gardner and H Rodriegez-Martinez and Michael W. Lane},
  journal={Human reproduction},
  year={1999},
  volume={14 10},
  pages={2575-80}
}
The effect of macromolecules on mouse embryo development and viability after culture in sequential media was investigated. It was found that high rates of viable blastocysts could be obtained in the absence of any macromolecule. Blastocyst cell numbers were increased when bovine serum albumin was present in the culture medium, although this benefit was not manifest after blastocyst transfer. Rather, the highest rates of implantation and fetal development after blastocyst transfer were observed… CONTINUE READING
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