Fetal cells in the maternal circulation.

  title={Fetal cells in the maternal circulation.},
  author={Wolfgang Holzgreve and Henk S. P. Garritsen and D Ganshirt-Ahlert},
  journal={The Journal of reproductive medicine},
  volume={37 5},
The analysis of fetal cells from the maternal circulation would be the least invasive method of prenatal diagnosis. Potential fetal cell types to enter the maternal circulation are lymphocytes, trophoblast cells and nucleated erythrocytes. With conventional methods, such as cytology and interphase or metaphase cytogenetics, the ratio of fetal to maternal cells was overestimated in the past. Currently most groups use polymerase chain reaction-based Y-sequence analysis for the detection of fetal… CONTINUE READING
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