Fetal bovine serum influences the stability and bioactivity of resveratrol analogues: A polyphenol-protein interaction approach.

@article{Tang2017FetalBS,
  title={Fetal bovine serum influences the stability and bioactivity of resveratrol analogues: A polyphenol-protein interaction approach.},
  author={Fen Tang and Yixi Xie and Hui Cao and Hua Yang and Xiaoqing Chen and Jianbo Xiao},
  journal={Food chemistry},
  year={2017},
  volume={219},
  pages={
          321-328
        }
}
Resveratrol Can Be Stable in a Medium Containing Fetal Bovine Serum with Pyruvate but Shortens the Lifespan of Human Fibroblastic Hs68 Cells
TLDR
Overall, the proposed method involving 10% FBS combined with pyruvate (1 mM) could completely prevent Res degradation, however, in contrast to the hypothesis, Res could induce the shortening of the lifespan of Hs68 cells.
Influence of Bovine Serum Albumin-Flavonoid Interaction on the Antioxidant Activity of Dietary Flavonoids: New Evidence from Electrochemical Quantification
TLDR
All the flavonoids show a decreasing in the antioxidant activity detected by CRAC assay, indicting a "masking effect" of bovine serum albumin (BSA)-flavonoid interaction.
Stability of dietary polyphenols: It's never too late to mend?
  • Jianbo Xiao
  • Biology
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association
  • 2018
Inhibition of resveratrol glucosides (REs) on advanced glycation endproducts (AGEs) formation: inhibitory mechanism and structure-activity relationship
TLDR
The results of antIGlycation mechanism showed that the antiglycation activity of REs was proportional to their antioxidant capacity and methylglyoxal (MGO) trapping capacity, and the REs are promising candidates worthy of further exploration for preventing AGEs accumulation in vivo, thereby treating A GEs-associated diseases.
Bioactivity of dietary polyphenols: The role of metabolites
TLDR
The present work strongly supports the contribution of metabolites to the health benefits of polyphenol, thus offering a better perspective in understanding the role played by dietary polyphenols in human health.
...
1
2
3
4
5
...

References

SHOWING 1-10 OF 34 REFERENCES
Stability of dietary polyphenols under the cell culture conditions: avoiding erroneous conclusions.
TLDR
The polyphenols were clearly more stable in human plasma than in DMEM, which may be caused by polyphenol-protein interactions, and it is strongly suggested to carry out stability tests in parallel with cell culture experiments for dietary antioxidants with catechol or pyrogallol structures and pyrog allol-type glycosides in order to avoid artifacts.
Compared Binding Properties between Resveratrol and Other Polyphenols to Plasmatic Albumin: Consequences for the Health Protecting Effect of Dietary Plant Microcomponents
TLDR
A role played by polyphenols-albumin interactions in the plasma for the bio-activities of these food microcomponents in the body is supported.
Stability of trans-resveratrol associated with transport proteins.
TLDR
The findings suggest that transport proteins are viable carriers to stabilize and deliver resveratrol in vivo in the biologically effective trans form.
Comparative studies of polydatin and resveratrol on mutual transformation and antioxidative effect in vivo.
Molecular structure-affinity relationship of natural polyphenols for bovine γ-globulin.
TLDR
The binding process with γ-globulin was strongly influenced by the structural differences of polyphenols, and Galloylated catechins and catechol-type catech ins exhibited higher binding affinities than non-galloylated and pyrogallol- type catech Ins.
A Review of Dietary Polyphenol-Plasma Protein Interactions: Characterization, Influence on the Bioactivity, and Structure-Affinity Relationship
  • Jianbo Xiao, G. Kai
  • Biology, Chemistry
    Critical reviews in food science and nutrition
  • 2012
TLDR
An overview of the research reports on the characterization, influence on the bioactivity, and the structure-affinity relationship for studying the affinities between polyphenols and plasma proteins is given.
Molecular property-affinity relationship of flavanoids and flavonoids for HSA in vitro.
TLDR
The affinities for HSA increased with increasing partition coefficients and decreased with increasing hydrogen bond donor and acceptor numbers of flava(o)noids, which suggested that the binding interaction was mainly caused by hydrophobic forces.
...
1
2
3
4
...