Fetal biometry of skeletal dysplasias: a multicentric study.

@article{Gonalves1994FetalBO,
  title={Fetal biometry of skeletal dysplasias: a multicentric study.},
  author={Lu{\'i}s Fl{\'a}vio de Andrade Gonçalves and Philippe Jeanty},
  journal={Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine},
  year={1994},
  volume={13 12},
  pages={977-85}
}
Twenty-three diagnostic centers worldwide contributed 127 cases of 17 skeletal dysplasias. Discriminant analysis showed that the femur length was the best biometric parameter to distinguish among the five most common disorders in this series (thanatophoric dysplasia, osteogenesis imperfecta type II, achondrogenesis, achondroplasia and hypochondroplasia). Fifty-four percent of fetuses with femur length below 30% of the mean for gestational age had achondrogenesis. Seventy-eight percent of… CONTINUE READING
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