Fetal and maternal candidate single nucleotide polymorphism associations with cerebral palsy: a case-control study.

@article{OCallaghan2012FetalAM,
  title={Fetal and maternal candidate single nucleotide polymorphism associations with cerebral palsy: a case-control study.},
  author={Michael E O'Callaghan and Alastair H Maclennan and Catherine S. Gibson and Gai L. McMichael and Eric Haan and Jessica L. Broadbent and Paul Nathan Goldwater and Jodie N Painter and Grant W. Montgomery and Gustaaf Dekker},
  journal={Pediatrics},
  year={2012},
  volume={129 2},
  pages={e414-23}
}
OBJECTIVE Previous studies have suggested associations between certain genetic variants and susceptibility to cerebral palsy (CP). This study was designed to assess established and novel maternal and child genetic and epidemiologic risk factors for CP along with their interactions. METHODS DNA from 587 case and 1154 control mother-child pairs was analyzed. A panel of 35 candidate single nucleotide polymorphisms (SNPs) were examined and included SNPs in genes associated with (1) thrombophilia… CONTINUE READING
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