Fetal and adult human skin fibroblasts display intrinsic differences in contractile capacity

@article{Moulin2001FetalAA,
  title={Fetal and adult human skin fibroblasts display intrinsic differences in contractile capacity},
  author={V{\'e}ronique J. Moulin and Betty Y. Y. Tam and G Castilloux and François A Auger and Maureen D. O’Connor-McCourt and Anie Philip and Lucie Germain},
  journal={Journal of Cellular Physiology},
  year={2001},
  volume={188}
}
One of the differences between fetal and adult skin healing is the unique ability of fetal wounds to heal without contracture and scar formation. Studies have shown that the ratio between the three isoforms of TGFβ is different in adult and fetal wounds. Thus, we analyzed the capacity of adult and fetal human skin fibroblasts to contract collagen gels after stimulation with TGFβ isoforms. In control medium, fetal fibroblasts had a contractile capacity similar to that of adult fibroblasts… 

The Contractile Phenotype of Dermal Fetal Fibroblasts in Scarless Wound Healing

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