Fetal alcohol exposure reduces serotonin innervation and compromises development of the forebrain along the serotonergic pathway.

@article{Zhou2005FetalAE,
  title={Fetal alcohol exposure reduces serotonin innervation and compromises development of the forebrain along the serotonergic pathway.},
  author={Feng Chao Zhou and Youssef Sari and Teresa A. Powrozek},
  journal={Alcoholism, clinical and experimental research},
  year={2005},
  volume={29 1},
  pages={141-9}
}
BACKGROUND We reported previously that a moderate level of fetal alcohol treatment reduces the birth, maturation, and migration of serotonin (5-HT) neurons at embryonic days 11 to 15 (E11-E15). Because 5-HT is known as a differentiation signal for forebrain development, we investigated whether alcohol affects 5-HT innervation to the developing brain and how the target brain areas grow as they receive 5-HT innervation between E15 and E18. METHODS Pregnant dams were divided into three groups… CONTINUE READING