Fetal Serum Lysosomal Enzymes

  title={Fetal Serum Lysosomal Enzymes},
  author={Aubrey Milunsky and Julian N. Kanfer and Fredric D Frigoletto},
  journal={Pediatric Research},
The difficulties and hazards of prolonged tissue culture (3-6 wks.) needed to establish the prenatal diagnoses of the hereditary biochemical disorders of metabolism are well recognized. Direct fetal blood sampling for study of lysosomal enzymes should allow the prenatal diagnosis of many ‘storage’ disorders within 24 hours of amniocentesis. The normal range… CONTINUE READING