Fetal Nucleic Acids in Maternal Plasma

  title={Fetal Nucleic Acids in Maternal Plasma},
  author={Y. Lo},
  journal={Annals of the New York Academy of Sciences},
  • Y. Lo
  • Published 2008
  • Medicine, Biology
  • Annals of the New York Academy of Sciences
  • The discovery of cell‐free fetal nucleic acids in maternal plasma has opened up new possibilities for noninvasive prenatal diagnosis. Over the last few years, a number of approaches have been demonstrated to allow such circulating fetal nucleic acids to be used for the prenatal detection of chromosomal aneuploidies. One such approach involves the enrichment of fetal DNA, such as by size fractionation or by the controversial formaldehyde treatment technique. A second approach involves the… CONTINUE READING

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