Fetal Hemodynamic Adaptive Changes Related to Intrauterine Growth: The Generation R Study

  title={Fetal Hemodynamic Adaptive Changes Related to Intrauterine Growth: The Generation R Study},
  author={Bero O. Verburg and Vincent W. V. Jaddoe and Juriy W. Wladimiroff and Albert Hofman and JacquelineC. M. Witteman and Eric A. P. Steegers},
Background— It has been suggested that an adverse fetal environment increases susceptibility to hypertension and cardiovascular disease in adult life. This increased risk may result from suboptimal development of the heart and main arteries in utero and from adaptive cardiovascular changes in conditions of reduced fetal growth. The aim of the present study was to evaluate whether reduced fetal growth is associated with fetal circulatory changes and cardiac dysfunction. Methods and Results— This… 

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