Fetal Fibroblasts and Keratinocytes with Immunosuppressive Properties for Allogeneic Cell-Based Wound Therapy

@inproceedings{Zuliani2013FetalFA,
  title={Fetal Fibroblasts and Keratinocytes with Immunosuppressive Properties for Allogeneic Cell-Based Wound Therapy},
  author={Thomas Zuliani and Soraya Saiagh and Anne-Chantal Knol and Julie Esbelin and Brigitte Dr{\'e}no},
  booktitle={PloS one},
  year={2013}
}
Fetal skin heals rapidly without scar formation early in gestation, conferring to fetal skin cells a high and unique potential for tissue regeneration and scar management. In this study, we investigated the possibility of using fetal fibroblasts and keratinocytes to stimulate wound repair and regeneration for further allogeneic cell-based therapy development. From a single fetal skin sample, two clinical batches of keratinocytes and fibroblasts were manufactured and characterized. Tolerogenic… CONTINUE READING
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