Fertilization antigen-1 removes antisperm autoantibodies from spermatozoa of infertile men and results in increased rates of acrosome reaction.


OBJECTIVE To determine if fertilization antigen (FA)-1 will remove autoantibodies from the surface of sperm cells of immunoinfertile men by immune adsorption and permit an increased acrosome reaction (AR). DESIGN Prospective analytic study. SETTING University medical center. PATIENT(S) Men from 18 infertile couples with autoantibodies present on their… (More)