Fertility options in young breast cancer survivors: a review of the literature.

@article{Dow2004FertilityOI,
  title={Fertility options in young breast cancer survivors: a review of the literature.},
  author={Karen Hassey Dow and D Kuhn},
  journal={Oncology nursing forum},
  year={2004},
  volume={31 3},
  pages={
          E46-53
        }
}
PURPOSE/OBJECTIVES To describe the impact of treatment on fertility, discuss fertility-sparing options available for women with breast cancer, and explore pregnancy subsequent to breast cancer. DATA SOURCES Published research, clinical articles, book chapters, and abstracts. DATA SYNTHESIS The risk of amenorrhea associated with alkylating agents in breast cancer survivors is well known. Fertility-sparing options before, during, and after treatment are possible with the use of assistive… 
View on PubMed
doi.org
43 Citations
Background Citations
12

43 Citations

Citation Type

Citation Type

The fertility-related concerns, needs and preferences of younger women with breast cancer: a systematic review
TLDR
The aim of the review is to identify the fertility-related needs, concerns and preferences of young women with early breast cancer and the databases MEDLINE and EMBASE were searched using keywords, and reference lists were examined.
Medical and Psychosocial Aspects of Fertility After Cancer
TLDR
Discussions of fertility issues in premenopausal women diagnosed with cancer present important challenges to the provider and to the patient, and physician education interventions should seek to improve the knowledge of fertility preservations options, and of locally and nationally available resources.
Cancer and its treatment effect on young breast cancer survivors.
The influence of endocrine effects of adjuvant therapy on quality of life outcomes in younger breast cancer survivors.
TLDR
This review identified adverse treatment outcomes for young and young midlife breast cancer survivors that can be minimized or prevented with targeted interventions.
Fertility preservation and breast cancer: a review
TLDR
This review aims to update the knowledge about the influence of breast cancer in fertility, the Influence of pregnancy and fertility preservation techniques in breast cancer patients and assessment of ovarian reserve for a better treatment choice.
Childbearing attitudes and decisions of young breast cancer survivors: a systematic review
TLDR
Clinicians may benefit from a deeper understanding of the importance of pregnancy and parenthood to survivors in order to provide the needed educational and psychosocial support services, overcome misinformation and better assist women with their fertility-related decisions.
Observational study of the development and evaluation of a fertility preservation patient decision aid for teenage and adult women diagnosed with cancer: the Cancer, Fertility and Me research protocol
TLDR
The overall aim of the ‘Cancer, Fertility and Me’ study is to develop and evaluate a new evidence-based patient decision aid (PtDA) for women with any cancer considering fertility preservation to address this unmet need.
Current evidence supporting fertility and pregnancy among young survivors of breast cancer.
TLDR
G gaps in care exist in the interdisciplinary evidence-based management of young survivors of breast cancer with fertility and parenting concerns after cancer treatment, according to national guidelines on fertility preservation.
Education and Support of Young Survivors of Breast Cancer Breast Cancer Diagnosis and Pretreatment
TLDR
The evidence is provided for (a) the effects of cancer treatment on gonadal function in young women with breast cancer, (b) national fertility guidelines and the role of breast cancer advocacy, (c) implications for nursing practice, and (d) future implications in interdisciplinary care of young womenWith breast cancer with concerns related to fertility and pregnancy.
Late and long-term effects of breast cancer treatment and surveillance management for the general practitioner.
TLDR
The clinician's role in cancer follow-up care is often poorly defined leading to a lack of awareness about the needs of survivors of breast cancer, suboptimal communication between providers and survivors, and an overall deficiency in quality care.
...
1
2
3
4
5
...

References

SHOWING 1-10 OF 40 REFERENCES
Fertility and the impact of systemic therapy on hormonal status following treatment for breast cancer
  • H. Moore
  • Medicine, Biology
    Current oncology reports
  • 2000
TLDR
Although nonhormonal therapies are available to manage many of the consequences of menopause, avoidance of chemotherapy-related ovarian toxicity may provide the best prospects for fertility after treatment.
Pregnancy after breast-conserving surgery and radiation therapy for breast cancer.
TLDR
Evaluated treatment outcome and quality of life among 23 breast cancer patients treated with conservative surgery and radiation and among 1624 patients treated at the Joint Center for Radiation Therapy between 1968 and 1985 who had subsequent pregnancies, results showed no differences in recurrence or distant metastasis between the matched groups.
Having children after breast cancer.
  • K. H. Dow
  • Medicine, Psychology
    Cancer practice
  • 1994
TLDR
Results indicate that pregnancy subsequent to breast cancer is a powerful stimulus for young women to "get well" again and explore the meaning of having children after breast cancer.
Ovarian function in premenopausal women treated with adjuvant chemotherapy for breast cancer.
  • J. Bines, D. Oleske, M. Cobleigh
  • Medicine, Biology
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology
  • 1996
TLDR
Ovarian damage is the most significant long-term sequela of adjuvant chemotherapy in premenopausal breast cancer survivors and a common definition of the following important terms is suggested: menopausal status, CRA (early and late), temporary CRA, and oligomenorrhea in the setting of adjUvant treatment.
Knowledge and experience regarding cancer, infertility, and sperm banking in younger male survivors.
TLDR
All men who are about to receive cancer treatment that could impair fertility should be counseled about such side effects and given adequate information to make an informed decision about banking sperm.
Should women be advised against pregnancy after breast-cancer treatment?
Effect of pregnancy on overall survival after the diagnosis of early-stage breast cancer.
  • S. Gelber, A. Coates, +7 authors R. Gelber
  • Medicine
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology
  • 2001
TLDR
Subsequent pregnancy does not adversely affect the prognosis of early-stage breast cancer and the superior survival seen in this and other controlled series may merely reflect a healthy patient selection bias, but is also consistent with an antitumor effect of the pregnancy.
The risk of premature menopause induced by chemotherapy for early breast cancer.
TLDR
Menstrual abnormalities and menopause will frequently occur in premenopausal early-stage breast cancer patients, with 30% of all patients amenorrheic 1 year after chemotherapy, suggesting ovarian failure.
The effects of radiotherapy and chemotherapy on female reproduction.
TLDR
Data on ovarian damage and failure following exposure to radiotherapy, chemotherapy and ablative therapy is presented and the mechanism of primordial follicles damage induced by radio/chemotherapy is presented as well as the role of apoptosis signalling pathways underlying destruction.
Risk of menopause during the first year after breast cancer diagnosis.
TLDR
Age and systemic chemotherapy are the strongest predictors of menopause in women with locoregional breast cancer as well as planned adjuvant treatment, and it may facilitate clinical decision-making.
...
1
2
3
4
...