Fertility in patients with congenital adrenal hyperplasia.

  title={Fertility in patients with congenital adrenal hyperplasia.},
  author={David E. Reichman and Perrin C White and Maria I. New and Zev Rosenwaks},
  journal={Fertility and sterility},
  volume={101 2},
Congenital adrenal hyperplasia (CAH) is the most frequently encountered genetic steroid disorder affecting fertility. Steroid hormones play a crucial role in sexual development and reproductive function; patients with either 21- hydroxylase or 11β-hydroxylase deficiency thus face immense challenges to their fertility. Given the relevance of CAH in reproductive medicine as well as the diagnostic challenges posed by the phenotypic overlap with polycystic ovary syndrome, we review the reproductive… CONTINUE READING
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