Fertile offspring derived from mammalian eggs lacking either animal or vegetal poles.

@article{ZernickaGoetz1998FertileOD,
  title={Fertile offspring derived from mammalian eggs lacking either animal or vegetal poles.},
  author={Magdalena Zernicka-Goetz},
  journal={Development},
  year={1998},
  volume={125 23},
  pages={
          4803-8
        }
}
In all animals so far tested, removing either pole of the undivided egg prevents normal development: embryos may arrest early, lack organs, or the adults may be sterile. These experiments have shown that spatial patterning of the egg is of utmost importance for subsequent development. However, the significance of spatial patterning in mammalian eggs is still controversial. To test the importance of egg polarity in the mouse a substantial amount of material either from the animal (polar body… CONTINUE READING
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