Ferritin synthesis in inflammation. I. Pathogenesis of impaired iron release.

@article{Konijn1977FerritinSI,
  title={Ferritin synthesis in inflammation. I. Pathogenesis of impaired iron release.},
  author={Abraham Marim Konijn and Chaim Hershko},
  journal={British journal of haematology},
  year={1977},
  volume={37 1},
  pages={7-16}
}
Plasma iron turnover (PIT) and ferritin synthesis in the liver and spleen were studied in rats within the first 24 h of inflammation produced by turpentine injection. Comparison of the sequential changes in PIT and ferritin synthesis showed that alterations in ferritin synthesis preceded the changes in plasma iron exchange throughout the study. Thus, after 4 h inflammation ferritin synthesis was twice normal whereas plasma iron and PIT were still unchanged. Conversely, maximal reduction in… CONTINUE READING

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