Ferritin H induction by histone deacetylase inhibitors.

@article{Wang2010FerritinHI,
  title={Ferritin H induction by histone deacetylase inhibitors.},
  author={Wei Wang and Xiumin Di and Suzy V. Torti and Frank M. Torti},
  journal={Biochemical pharmacology},
  year={2010},
  volume={80 3},
  pages={316-24}
}
Because both iron deficiency and iron excess are deleterious to normal cell function, the intracellular level of iron must be tightly controlled. Ferritin, an iron binding protein, regulates iron balance by storing iron in a bioavailable but nontoxic form. Ferritin protein comprises two subunits: ferritin H, which contains ferroxidase activity, and ferritin L. Here we demonstrate that ferritin H mRNA and protein are induced by histone deacetylase inhibitors (HDAC inhibitors), a promising class… CONTINUE READING

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References

Publications referenced by this paper.
Showing 1-10 of 49 references

Posttranslational regulation of NF-YA modulates NF-Y transcriptional activity.

Molecular biology of the cell • 2008
View 4 Excerpts
Highly Influenced

Role of histone deacetylation in cell-specific expression of endothelial nitric-oxide synthase.

The Journal of biological chemistry • 2005
View 3 Excerpts
Highly Influenced

Histone deacetylase inhibitors: mechanism of action and therapeutic use in cancer.

Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico • 2008
View 1 Excerpt

Iron chelation in the biological activity of curcumin.

Free radical biology & medicine • 2006
View 1 Excerpt

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