Corpus ID: 44202607

Fermented Ginseng Attenuates Hepatic Lipid Accumulation and Hyperglycemia through AMPK Activation

@article{Kim2009FermentedGA,
  title={Fermented Ginseng Attenuates Hepatic Lipid Accumulation and Hyperglycemia through AMPK Activation},
  author={Do Yeon Kim and J. Park and Hai-Dan Yuan and S. Chung},
  journal={Food Science and Biotechnology},
  year={2009},
  volume={18},
  pages={172-178}
}
Fermented ginseng (FG) is an ethanol extract of ginseng radix processed with β-galactosidase. It was hypothesized that FG may exert anti-hyperlipidemic and anti-diabetic activities through modulating AMP-activated protein kinase (AMPK) in HepG2 human hepatoma cells. In this study, we showed that AMPK phosphorylation was stimulated by FG. These effects were abolished by pretreatment with an AMPK inhibitor, compound C. In addition, FG regulated the expression of genes associated with lipogenesis… Expand
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