Fermentative Production of Cysteine by Pantoea ananatis

@article{Takumi2016FermentativePO,
  title={Fermentative Production of Cysteine by Pantoea ananatis},
  author={Kazuhiro Takumi and Mikhail Kharisovich Ziyatdinov and V. V. Samsonov and Gen Nonaka},
  journal={Applied and Environmental Microbiology},
  year={2016},
  volume={83}
}
ABSTRACT Cysteine is a commercially important amino acid; however, it lacks an efficient fermentative production method. Due to its cytotoxicity, intracellular cysteine levels are stringently controlled via several regulatory modes. Managing its toxic effects as well as understanding and deregulating the complexities of regulation are crucial for establishing the fermentative production of cysteine. The regulatory modes include feedback inhibition of key metabolic enzymes, degradation, efflux… Expand
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