Fenvalerate, a pyrethroid insecticide, adversely affects sperm production and storage in male rats.

  title={Fenvalerate, a pyrethroid insecticide, adversely affects sperm production and storage in male rats.},
  author={Arielle Cristina Arena and Carla Dal Bianco Fernandez and Elaine Manoela Porto and Denise Z Bissacot and Oduvaldo C{\^a}mara Marques Pereira and W G Kempinas},
  journal={Journal of toxicology and environmental health. Part A},
  volume={71 23},
The aim of this study was to investigate the potential estrogenic activity of fenvalerate by examining reproductive and fertility capabilities in Wistar rats. Adult male animals were treated for 30 d with 20 or 40 mg/kg/d fenvalerate or corn oil (vehicle) by oral gavage. Further, a possible estrogenic activity of fenvalerate (0.4, 1, 4, 8, or 40 mg/kg) was tested after a 3-d treatment of immature female rats using the uterotrophic assay. Exposure to the higher dose of fenvalerate was toxic to… CONTINUE READING


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