Fentanyl receptor assay. II. Utilization of a radioreceptor assay for the analysis of fentanyl analogs in urine.

@article{Alburges1992FentanylRA,
  title={Fentanyl receptor assay. II. Utilization of a radioreceptor assay for the analysis of fentanyl analogs in urine.},
  author={M. Alburges and G. Hanson and J. Gibb and C. Sakashita and D. Rollins},
  journal={Journal of analytical toxicology},
  year={1992},
  volume={16 1},
  pages={
          36-41
        }
}
  • M. Alburges, G. Hanson, +2 authors D. Rollins
  • Published 1992
  • Chemistry, Medicine
  • Journal of analytical toxicology
  • A radioreceptor assay has been developed to measure fentanyl and fentanyl-like drugs in biological specimens. The assay is based on the competition of these drugs with [3H]fentanyl for opioid receptors. Rats were injected intravenously with fentanyl (15 micrograms/kg), alpha-methylfentanyl (15 micrograms/kg), (+/-)-cis-3-methylfentanyl (15 micrograms/kg), butyrylfentanyl (0.48 mg/kg), and benzylfentanyl (3.19 mg/kg). Urine samples were analyzed by radioreceptor assay (RRA), radioimmunoassay… CONTINUE READING
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