Fentanyl nasal spray for the treatment of cancer pain.

  title={Fentanyl nasal spray for the treatment of cancer pain.},
  author={Kyriaki Mystakidou and Irene Panagiotou and Athanassios D Gouliamos},
  journal={Expert opinion on pharmacotherapy},
  volume={12 10},
INTRODUCTION Breakthrough pain, a transitory flare of pain in patients with otherwise controlled chronic pain, has been well characterized in cancer patients but despite medical awareness, sometimes remains underdiagnosed and therefore undertreated. AREAS COVERED Oral transmucosal fentanyl citrate (OTFC) and fentanyl buccal tablets are the first medications developed specifically for the treatment of breakthrough pain in opioid-tolerant patients. Since oral administration of fentanyl is not… CONTINUE READING


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