• Corpus ID: 27364898

Fentanyl nasal spray (Lazanda) for pain.

@article{2011FentanylNS,
  title={Fentanyl nasal spray (Lazanda) for pain.},
  author={},
  journal={The Medical letter on drugs and therapeutics},
  year={2011},
  volume={53 1379-1380},
  pages={
          99-100
        }
}
  • Published 2011
  • Medicine
  • The Medical letter on drugs and therapeutics
The FDA has approved a nasal spray formulation of fentanyl (Lazanda-Archimedes) for management of breakthrough pain in adult cancer patients who are already receiving and are tolerant to opioid therapy. Fentanyl is already available in the US for intravenous, intrathecal, epidural, transdermal and oral transmucosal use. 
1 Citations
Intranasal fentanyl spray versus intravenous opioids for the treatment of severe pain in patients with cancer in the emergency department setting: A randomized controlled trial
TLDR
Two of three analyses supported non-inferiority of INF versus IVH, while one analysis was inconclusive, and INF had the advantage of shorter time to administration.