Fentanyl-induced seizures activate subcortical brain metabolism.

@article{Tommasino1984FentanylinducedSA,
  title={Fentanyl-induced seizures activate subcortical brain metabolism.},
  author={Concezione Tommasino and Tsuyoshi Maekawa and Heather M Shapiro and J Keifer-Goodman and R W Kohlenberger},
  journal={Anesthesiology},
  year={1984},
  volume={60 4},
  pages={283-90}
}
Neurophysiologic studies have demonstrated epileptoid activity during high-dose narcotic anesthesia. The authors utilized the 14C-2-deoxyglucose method to evaluate the local cerebral glucose metabolism (l-CMRg) during high-dose fentanyl-induced epileptoid discharges as evaluated by electroencephalography (EEG) in ventilated rats. Fentanyl was administered… CONTINUE READING