Femtogram detection limits for biogenic amines using microbore HPLC with electrochemical detection.

@article{Caliguri1984FemtogramDL,
  title={Femtogram detection limits for biogenic amines using microbore HPLC with electrochemical detection.},
  author={E J Caliguri and Ivan N. Mefford},
  journal={Brain research},
  year={1984},
  volume={296 1},
  pages={156-9}
}
Detection limits for biogenic amines, serotonin (5-HT), 5-hydroxyindoleacetic acid, 5-hydroxytryptophan, norepinephrine, epinephrine, dopamine and 3,4-dihydroxyphenylacetic acid (DOPAC), of 50-200 fg are reported. This was accomplished using microbore HPLC with electrochemical detection. Reproducibility at the 1-5 pg level of 1.6-8.1% was obtained. The… CONTINUE READING