Feminizing chicks: a model for avian sex determination based on titration of Hint enzyme activity and the predicted structure of an Asw-Hint heterodimer

@article{Pace2002FeminizingCA,
  title={Feminizing chicks: a model for avian sex determination based on titration of Hint enzyme activity and the predicted structure of an Asw-Hint heterodimer},
  author={Helen C Pace and Charles Brenner},
  journal={Genome Biology},
  year={2002},
  volume={4},
  pages={R18 - R18}
}
In birds and some lizards, females are heterogametic with a ZW karyotype, while males are ZZ homogametes. The molecular basis for sexual differentiation in birds is unknown: arguments exist for doses of Z masculinizing chicks and for W information feminizing. ASW was identified as a tandemly repeated gene conserved on avian W chromosomes that is expressed in early female development and appears to be an inactive form of avian Z-encoded HINT. Hint is a dimeric enzyme that hydrolyzes AMP linked… CONTINUE READING
20 Citations
44 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 20 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 44 references

co m m nt rview s rpo ts depo sted rearch intractio ns fo rm atio n rereed rearch http://genomebiology.com/2003/4/3/R18 Genome Biology 2003, Volume 4, Issue 3, Article R18 Pace and Brenner R18.5

  • S Barbaux, P Niaudet, +7 authors M Fellous
  • Genome Biology
  • 2003
2 Excerpts

Similar Papers

Loading similar papers…