Female sticklebacks count alleles in a strategy of sexual selection explaining MHC polymorphism

@article{Reusch2001FemaleSC,
  title={Female sticklebacks count alleles in a strategy of sexual selection explaining MHC polymorphism},
  author={Thorsten B. H. Reusch and M. A. H{\"a}berli and Peter Aeschlimann and Manfred Milinski},
  journal={Nature},
  year={2001},
  volume={414},
  pages={300-302}
}
The origin and maintenance of polymorphism in major histocompatibility complex (MHC) genes in natural populations is still unresolved. Sexual selection, frequency-dependent selection by parasites and pathogens, and heterozygote advantage have been suggested to explain the maintenance of high allele diversity at MHC genes. Here we argue that there are two (non-exclusive) strategies for MHC-related sexual selection, representing solutions to two different problems: inbreeding avoidance and… Expand
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