Female-specific features of recombinational double-stranded DNA repair in relation to synapsis and telomere dynamics in human oocytes

@article{Roig2004FemalespecificFO,
  title={Female-specific features of recombinational double-stranded DNA repair in relation to synapsis and telomere dynamics in human oocytes},
  author={Ignasi Roig and Bodo Liebe and J J Egozcue and Ll. Cabero and Montserrat Garc{\'i}a and Harry Scherthan},
  journal={Chromosoma},
  year={2004},
  volume={113},
  pages={22-33}
}
Chromosome segregation errors are a significant cause of aneuploidy among human neonates and often result from errors in female meiosis that occur during fetal life. For the latter reason, little is known about chromosome dynamics during female prophase I. Here, we analyzed chromosome reorganization, and centromere and telomere dynamics in meiosis in the human female by immunofluorescent staining of the SYCP3 and SYCP1 synaptonemal complex proteins and the course of recombinational DNA repair… CONTINUE READING