Female reproductive steroids and neuronal excitability

@article{Finocchi2011FemaleRS,
  title={Female reproductive steroids and neuronal excitability},
  author={C. Finocchi and M. Ferrari},
  journal={Neurological Sciences},
  year={2011},
  volume={32},
  pages={31-35}
}
  • C. Finocchi, M. Ferrari
  • Published 2011
  • Biology, Medicine
  • Neurological Sciences
  • Oestrogen and progesterone have specific receptors in the central nervous system and are able to regulate neuronal development and plasticity, neuronal excitability, mitochondrial energy production, and neurotransmitter synthesis, release, and transport. On neuronal excitability, estradiol and progesterone seem to have an opposite effect, with estradiol being excitatory and progesterone and its derivative allopregnanolone being inhibitory. Estradiol augments N-methyl-d-aspartate-mediated… CONTINUE READING
    68 Citations
    Sex and the migraine brain
    • 45
    Neuroendocrine considerations in the treatment of men and women with epilepsy
    • 76
    Novel anticonvulsive effects of progesterone in a mouse model of hippocampal electrical kindling
    • 15
    Allopregnanolone as a mediator of affective switching in reproductive mood disorders
    • 61
    Serum levels of allopregnanolone, progesterone and testosterone in menstrually-related and postmenopausal migraine: A cross-sectional study
    Neurovascular Pharmacology of Migraine: Epigenetics and Sex Hormones
    • PDF

    References

    SHOWING 1-10 OF 44 REFERENCES
    Effects of ovarian hormones on human cortical excitability
    • 244
    Neuroactive Properties of Reproductive Steroids
    • 31
    • Highly Influential
    The role of sex steroids in catamenial epilepsy and premenstrual dysphoric disorder: Implications for diagnosis and treatment
    • 29
    • Highly Influential
    Menstrual cycle effects on cortical excitability
    • 284
    Estrogen administration increases neuronal responses to excitatory amino acids as a long-term effect
    • S. Smith
    • Biology, Medicine
    • Brain Research
    • 1989
    • 186
    Pathogenesis in Menstrual Cycle‐Linked CNS Disorders
    • 144
    Invited review: Estrogens effects on the brain: multiple sites and molecular mechanisms.
    • B. McEwen
    • Biology, Medicine
    • Journal of applied physiology
    • 2001
    • 587