Female odors lead to rapid activation of mitogen-activated protein kinase (MAPK) in neurons of the vomeronasal system.

@article{Dudley2001FemaleOL,
  title={Female odors lead to rapid activation of mitogen-activated protein kinase (MAPK) in neurons of the vomeronasal system.},
  author={Carol A. Dudley and Sarvajit Chakravarty and Ayalla Barnea},
  journal={Brain research},
  year={2001},
  volume={915 1},
  pages={32-46}
}
Pheromonal mediation of reproductive function proceeds along a neuroanatomical pathway that connects the vomeronasal organ (VNO) at the periphery with downstream target-sites in the amygdala and hypothalamus. The MAPK pathway is a prominent cascade linking receptor activation to induction of effectors such as c-Fos. We addressed the question: Does a specific pheromone stimulus lead to activation (phosphorylation, P) of MAPK in the VN system of the male mouse? Phosphorylation of MAPK in the VN… CONTINUE READING