Female Hormonal Factors and the Risk of Endometrial Cancer in Lynch Syndrome.

@article{Dashti2015FemaleHF,
  title={Female Hormonal Factors and the Risk of Endometrial Cancer in Lynch Syndrome.},
  author={Seyedeh Ghazaleh Dashti and Rowena Chau and Driss Ait Ouakrim and Daniel D Buchanan and Mark Clendenning and Joanne P. Young and Ingrid M Winship and Julie Arnold and Dennis J. Ahnen and Robert W Haile and Graham R Casey and Steven Gallinger and Stephen N. Thibodeau and Noralane M. Lindor and Lo{\"i}c Le Marchand and Polly A Newcomb and John D. Potter and John A. Baron and John L. Hopper and Mark A Jenkins and Aung Ko Win},
  journal={JAMA},
  year={2015},
  volume={314 1},
  pages={61-71}
}
IMPORTANCE Apart from hysterectomy, there is no consensus recommendation for reducing endometrial cancer risk for women with a mismatch repair gene mutation (Lynch syndrome). OBJECTIVE To investigate the association between hormonal factors and endometrial cancer risk in Lynch syndrome. DESIGN, SETTING, AND PARTICIPANTS A retrospective cohort study included 1128 women with a mismatch repair gene mutation identified from the Colon Cancer Family Registry. Data were analyzed with a weighted… CONTINUE READING

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